hrp0097p1-489 | GH and IGFs | ESPE2023

Effects of GH therapy in patients with GHD (Growth Hormone Deficiency) on glucose homeostasis: results of a 10-years follow-up

Vasaturo Sara , Illiano Sara , Mirra Rita , Lorello Paola , Apuzzo Diletta , Di Mase Raffaella , Capalbo Donatella , Salerno Mariacarolina

Objectives: Among adverse effects of GH, a particular attention should be given to glucose homeostasis. The aim of the study was evaluate the effect of GH therapy on glucose homeostasis in children with GHD after 10 years of treatment.Methods: 30 patients (8 M/22 F, age 7.00 ± 2.61 years) with GHD at diagnosis and 30 healthy children comparable to patients for age, sex and BMI were enrolled. Glucose, insulin, HOMA-IR ...